Whilst brain tumours are more common with increasing age, they are a particularly important in children and young adults, since they make up a greater proportion of all cancers in this age group and are often difficult to treat. Cancer is the most common cause of death from disease in children and brain tumours are the most common solid tumours in this age group. Around 1 in 700 children are diagnosed with cancer and so most children will know of someone who has it from school.
Whilst there have been impressive improvements in the outcome of children with cancer with around 75% projected to become long term survivors now compared with only 10% about 60 years ago, these improvements have not been matched for children with brain tumours with about 60% becoming long term survivors. Due to this, brain tumours are now the most common cause of death from cancer in children and young people. Many brain tumours are readily treatable, however, some have a very poor outcome with almost no survivors. Clearly we have a long way to go in both understanding and treating these diseases.
One of the major challenges of treating brain tumours is that those who survive often live with a dreadful burden of disability. Problems can affect many different aspects with mobility, co-ordination, eyesight and hearing all at risk. Children are often particularly poorly effected since their brain is still developing and there is a particular problem with the effect of the tumour and its treatment on learning. We have come a long way in our understanding of many brain tumours and our ability to treat them but there is clearly still a long way to go.
They have pioneered the use of imaging methods to probe tumour properties directly in the patients and use this to help diagnose and understand brain tumours as well as optimise their treatment. The improved understanding of the tumours both in the patients and in the laboratory is leading to ways of optimising current treatments as well as the discovery of new ways which are promising for the treatment of aggressive brain tumours. Unparalleled facilities are available for the research with the newly opened National Institute for Health Research 3T MRI Research Centre at Birmingham Children’s Hospital and the School of Cancer Sciences at the University of Birmingham. It is essential that advances are made available to all patients and we lead national and international networks to ensure that this happens quickly and efficiently. In addition to the above, our advisory board of specialists help us to target funding where it is most needed. If your programme or team are looking for our help please see grant options below.
HHHO and our medical research team are happy to award large grants to cover research into brain tumours which may cover sponsorship of PhD Students or fund vital equipment and consumables etc that are required to undertake the work.
If you wish to apply for a large research grant please contact Georgie@hhho.org.uk with a full overview of your grant request. This should include a full explanation of the research you wish to undertake, how and why you wish to undertake this work, what you are hoping to achieve from this piece of work and the value / impact you are hoping to achieve. A full breakdown of costs to cover the research would also be required.
We aim to be as reactive as possible.You will have a decision within a maximum of 28 days.All cheques will be paid to the employing Institution.A one page report outlining the research which has been undertaken using the grant must be submitted within 6 months of receiving the grant.Any conference abstracts, presentations or paper publications which result from the grant must include recognition of the funding.Awardees must agree to meet with representatives of HHHO if this is requested.Applicants must have an employment contract with their host institution for at least 1 year from the date of the award.Only one application can be made by an applicant per year.
A one page application form completed on the appropriate template should be submitted by email to firstname.lastname@example.org
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